Concepedia

Th17 Cell Differentiation

Th17 Cell Differentiation is a biological process in which naïve CD4+ T cells develop into the Th17 subset through the coordinated action of specific cytokines and transcription factors, distinguished by the production of interleukin-17 and its role in mediating autoimmune inflammation.

3.6K

Publications

351.2K

Citations

22.5K

Authors

3.3K

Institutions

Publications per year

2017–2026

1.4K

Parents

Publications

3.6K

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Estelle Bettelli, Yijun Carrier, Wenda Gao et al. · Nature · 2006 · 6.9K citations

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The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

Ivaylo I. Ivanov, Brent S. McKenzie, Liang Zhou et al. · Cell · 2006 · 5.1K citations · Full text

, , +16

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

Ivaylo I. Ivanov, Koji Atarashi, Nicolas Manel et al. · Cell · 2009 · 4.5K citations · Full text

, , +14

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

Heon Park, Zhaoxia Li, Xuexian O. Yang et al. · Nature Immunology · 2005 · 4.2K citations · Full text

, , +17

TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

Marc Veldhoen, Richard J. Hocking, Christopher J. Atkins et al. · Immunity · 2006 · 3.6K citations · Full text

, , +12

1–5 of 3.6K

Authors

22.5K

  1. VK
    Vijay K. Kuchroo

    Brigham and Women's Hospital, United States

    43 publications · 20K citations

    37

    h-index

  2. MC
    Mi‐La Cho

    Catholic University of Korea, South Korea

    55 publications · 2.8K citations

    34

    h-index

  3. YI
    Yoichiro Iwakura

    Tokyo University of Science, Japan

    36 publications · 8.6K citations

    30

    h-index

  4. SP
    Sung‐Hwan Park

    Catholic University of Korea, South Korea

    39 publications · 2.2K citations

    29

    h-index

  5. CD
    Chen Dong

    The University of Texas MD Anderson Cancer Center, United States

    32 publications · 12.5K citations

    28

    h-index

1–5 of 22.5K

Institutions

3.3K

  1. Harvard University

    Cambridge, United States

    82 h-index

    714 publications

    192.1K citations

  2. National Institutes of Health

    Bethesda, United States

    65 h-index

    455 publications

    134.7K citations

  3. Brigham and Women's Hospital

    Boston, United States

    58 h-index

    367 publications

    159.4K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    52 h-index

    105 publications

    67.2K citations

  5. Inserm

    Paris, France

    52 h-index

    594 publications

    71.5K citations

  6. Shanghai Jiao Tong University

    Shanghai, China

    43 h-index

    392 publications

    25.4K citations

  7. New York University

    New York, United States

    39 h-index

    206 publications

    124.8K citations

  8. The University of Tokyo

    Tokyo, Japan

    38 h-index

    155 publications

    41.7K citations

1–8 of 3.3K

Venues

  1. The Journal of Immunology

    JI · 371 publications · 37.3K citations

    105

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 122 publications · 15.9K citations

    62

    h-index

  3. The Journal of Experimental Medicine

    63 publications · 15.8K citations

    53

    h-index

  4. Immunity

    53 publications · 24.1K citations

    50

    h-index

  5. Nature Immunology

    52 publications · 28.5K citations

    49

    h-index

1–5