The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

Ivaylo I. Ivanov, Brent S. McKenzie, Liang Zhou, +5

Cell

InflammationCytokineLymphocyte DevelopmentImmune RegulationImmunology +7

IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

Liang Zhou, Ivaylo I. Ivanov, Rosanne Spolski, +6

Nature Immunology

InflammationCytokineAutoimmune DiseaseImmune Cell DevelopmentIl-23 Pathways +7

TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function

Liang Zhou, Jared E. Lopes, Mark M. W. Chong, +9

Nature

Transcriptional RegulationSignaling PathwayLymphocyte DevelopmentImmune Cell DevelopmentT-regulatory Cell +9

Plasticity of CD4+ T Cell Lineage Differentiation

Liang Zhou, Mark M. W. Chong, Dan R. Littman

Immunity

Cell SpecializationCell BiologyLineage PlasticityLymphocyte Development

The Aryl Hydrocarbon Receptor Regulates Gut Immunity through Modulation of Innate Lymphoid Cells

Ju Qiu, Jennifer J. Heller, Xiaohuan Guo, +4

Immunity

InflammationAutoimmune DiseaseAllergyMucosal ImmunologyInnate Lymphoid Cells +6

Commensal bacteria protect against food allergen sensitization

Andrew Stefka, Taylor Feehley, Prabhanshu Tripathi, +12

Proceedings of the National Academy of Sciences

Food AllergyDysbiosisImmunologyAllergenGut Microbiology +15

Group 3 Innate Lymphoid Cells Inhibit T-Cell-Mediated Intestinal Inflammation through Aryl Hydrocarbon Receptor Signaling and Regulation of Microflora

Ju Qiu, Xiaohuan Guo, Zongming E. Chen, +5

Immunity

InflammationMucosal ImmunologyInnate Immune SystemImmunologyGastroenterology +6

Induction of Innate Lymphoid Cell-Derived Interleukin-22 by the Transcription Factor STAT3 Mediates Protection against Intestinal Infection

Xiaohuan Guo, Ju Qiu, Tony Tu, +5

Immunity

InflammationCytokineMucosal ImmunologyInnate Immune SystemImmunology +6

Expression of RORγt Marks a Pathogenic Regulatory T Cell Subset in Human Colon Cancer

Nichole R. Blatner, Mary F. Mulcahy, Kristen L. Dennis, +21

Science Translational Medicine

Aryl Hydrocarbon Receptor Signaling Cell Intrinsically Inhibits Intestinal Group 2 Innate Lymphoid Cell Function

Shiyang Li, John W. Bostick, Jian Ye, +5

Immunity

InflammationAutoimmune DiseaseMucosal ImmunologyInnate Immune SystemImmunology +6