Kristen Pollizzi

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2

Greg M. Delgoffe, Kristen Pollizzi, Adam T. Waickman et al. · Nature Immunology · 2011 · 1.1K citations · Full text

Kinase Mtor, Signal Transduction, Signaling Pathway +8

Response of a Neuronal Model of Tuberous Sclerosis to Mammalian Target of Rapamycin (mTOR) Inhibitors: Effects on mTORC1 and Akt Signaling Lead to Improved Survival and Function

Lynsey M. Meikle, Kristen Pollizzi, Anna Egnor et al. · Journal of Neuroscience · 2008 · 500 citations · Full text

A Mouse Model of Tuberous Sclerosis: Neuronal Loss of Tsc1 Causes Dysplastic and Ectopic Neurons, Reduced Myelination, Seizure Activity, and Limited Survival

Lynsey M. Meikle, Delia M. Talos, Hiroaki Onda et al. · Journal of Neuroscience · 2007 · 456 citations · Full text

Brain Development, Neurological Disorder, Neurobiology Of Disease +16

mTORC1 and mTORC2 selectively regulate CD8+ T cell differentiation

Kristen Pollizzi, Chirag H. Patel, Im‐Hong Sun et al. · Journal of Clinical Investigation · 2015 · 401 citations · Full text

Immunological Memory, Mtor Complex 1, Signal Transduction +12

Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8+ T cell differentiation

Kristen Pollizzi, Im‐Hong Sun, Chirag H. Patel et al. · Nature Immunology · 2016 · 223 citations · Full text

Signal Transduction, Signaling Pathway, Cell Division +10