Concepedia

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2

Greg M. Delgoffe, Kristen Pollizzi, Adam T. Waickman, Emily Heikamp, David J. Meyers, Maureen R. Horton, Bo Xiao, Paul F. Worley, Jonathan D. Powell

Nature Immunology · 2011 · 1.1K citations · 42 references

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42

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

Heon Park, Zhaoxia Li, Xuexian O. Yang et al. · Nature Immunology · 2005 · 4.2K citations · Full text

, , +17

mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery

Do‐Hyung Kim, Dos D. Sarbassov, Siraj M. Ali et al. · Cell · 2002 · 3K citations · Full text

, , +14

Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton

Dos D. Sarbassov, Siraj M. Ali, Do‐Hyung Kim et al. · Current Biology · 2004 · 2.7K citations · Full text

, , +12

Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB

Dos D. Sarbassov, Siraj M. Ali, Shomit Sengupta et al. · Molecular Cell · 2006 · 2.6K citations · Full text

, , +6

PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

Loise M. Francisco, Victor H. Salinas, Keturah Brown et al. · The Journal of Experimental Medicine · 2009 · 2K citations · Full text

, , +16