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Targeting the intracellular immune checkpoint CISH with CRISPR-Cas9-edited T cells in patients with metastatic colorectal cancer: a first-in-human, single-centre, phase 1 trial

Cancer ImmunosurveillanceMedicineImmunologyColorectal CancerMetastatic Colorectal CancerImmune Checkpoint InhibitorCrispr-cas9-edited T CellsImmune Cell TherapyImmunotherapyOncologyRadiation Oncology