Geoffrey Guittard

Ionic immune suppression within the tumour microenvironment limits T cell effector function

Robert Eil, Suman K. Vodnala, David Clever et al. · Nature · 2016 · 658 citations · Full text

Ionic Immune Suppression, Immune Evasion, Cancer Immunosurveillance +11

Cish actively silences TCR signaling in CD8+ T cells to maintain tumor tolerance

Douglas C. Palmer, Geoffrey Guittard, Zulmarie Franco et al. · The Journal of Experimental Medicine · 2015 · 191 citations · Full text

Vitamin D Controls Tumor Growth and CD8+ T Cell Infiltration in Breast Cancer

Esma Karkeni, Stéphanie O. Morin, Berna Bou Tayeh et al. · Frontiers in Immunology · 2019 · 78 citations · Full text

Targeting CISH enhances natural cytotoxicity receptor signaling and reduces NK cell exhaustion to improve solid tumor immunity

P Bernard, Rebecca B. Delconte, Sonia Pastor et al. · Journal for ImmunoTherapy of Cancer · 2022 · 62 citations · Full text

Cutting Edge: Dok-1 and Dok-2 Adaptor Molecules Are Regulated by Phosphatidylinositol 5-Phosphate Production in T Cells

Geoffrey Guittard, Audrey Gérard, Sophie Dupuis-Coronas et al. · The Journal of Immunology · 2009 · 57 citations · Full text

Phosphatidylinositol 5-Phosphate Production, Signal Transduction, Cell Regulation +14