Cish actively silences TCR signaling in CD8+ T cells to maintain tumor tolerance

Douglas C. Palmer, Geoffrey Guittard, Zulmarie Franco, +17

The Journal of Experimental Medicine

miR-155 augments CD8 ⁺ T-cell antitumor activity in lymphoreplete hosts by enhancing responsiveness to homeostatic γ _c cytokines

Yun Ji, Claudia Wrzesinski, Zhiya Yu, +14

Proceedings of the National Academy of Sciences

Impact of Prior Treatment on the Efficacy of Adoptive Transfer of Tumor-Infiltrating Lymphocytes in Patients with Metastatic Melanoma

Samantha J. Seitter, Richard M. Sherry, James Chih‐Hsin Yang, +12

Clinical Cancer Research

An Efficient Single-Cell RNA-Seq Approach to Identify Neoantigen-Specific T Cell Receptors

Yong‐Chen Lu, Zhili Zheng, Paul F. Robbins, +9

Molecular Therapy

EngineeringT-regulatory CellImmunologyImmunoeditingTranscriptomics Technology +25

Identification of the Genomic Insertion Site of Pmel-1 TCR α and β Transgenes by Next-Generation Sequencing

Yun Ji, Natalie Abrams, Wei Zhu, +9

PLoS ONE

Transgenic Mouse ModelsLaboratory ImmunologyGeneticsImmunologyMolecular Biology +21

Type I Cytokines Synergize with Oncogene Inhibition to Induce Tumor Growth Arrest

Nicolas Acquavella, David Clever, Zhiya Yu, +24

Cancer Immunology Research

ImmunologyImmunoeditingImmunotherapeuticsImmune Cell TherapyImmunotherapy +22

Blood reference materials from macaques infected with variant <scp>C</scp>reutzfeldt‐<scp>J</scp>akob disease agent

Kristy L. McDowell, Nabanita Nag, Zulmarie Franco, +7

Transfusion

Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade

Douglas C. Palmer, Beau R. Webber, Yogin Patel, +35

Internal CheckpointTil SenescenceImmunologyImmune RegulationImmunoediting +18

333 Targeting the apical intracellular checkpoint CISH unleashes T cell neoantigen reactivity and effector program

Douglas C. Palmer, Beau R. Webber, Yogin Patel, +35

Regular and Young Investigator Award Abstracts

ImmunologyImmunoeditingImmunotherapeuticsImmune Cell TherapyCancer Biology +16

Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade

Douglas C. Palmer, Beau R. Webber, Yogin Patel, +35

Internal CheckpointTil SenescenceImmunologyImmune RegulationImmunoediting +19