Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer

Eric Tran, Simon Turcotte, Alena Gros, +10

Science

T-regulatory CellImmunologyPathologyEpithelial CancerImmune Cell Therapy +20

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

Eric Tran, Paul F. Robbins, Yong‐Chen Lu, +8

New England Journal of Medicine

Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells

Paul F. Robbins, Yong‐Chen Lu, Mona El‐Gamil, +9

Nature Medicine

Tumor BiologyTumor-reactive T CellsCancer ImmunosurveillanceTumor HeterogeneityMedicine +11

Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer

Nikolaos Zacharakis, Harshini Chinnasamy, Mary A. Black, +14

Nature Medicine

Durable RegressionMetastatic Breast CancerEngineeringSomatic VariantBreast Oncology +11

Immunogenicity of somatic mutations in human gastrointestinal cancers

Eric Tran, Mojgan Ahmadzadeh, Yong‐Chen Lu, +10

Science

Cancer ImmunosurveillanceSomatic VariantSomatic MutationsGastrointestinal OncologyHuman Immune System +13

Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers

Frank J. Lowery, Sri Krishna, Rami Yossef, +39

Science

Efficient Identification of Mutated Cancer Antigens Recognized by T Cells Associated with Durable Tumor Regressions

Yong‐Chen Lu, Xin Yao, Jessica S. Crystal, +9

Clinical Cancer Research

Pilot Trial of Adoptive Transfer of Chimeric Antigen Receptor–transduced T Cells Targeting EGFRvIII in Patients With Glioblastoma

Stephanie L. Goff, Richard A. Morgan, James C. Yang, +14

Journal of Immunotherapy

Deletion VariantCell TherapyImmunologyImmunoeditingImmunotherapeutics +22

Treatment of Patients With Metastatic Cancer Using a Major Histocompatibility Complex Class II–Restricted T-Cell Receptor Targeting the Cancer Germline Antigen MAGE-A3

Yong‐Chen Lu, Linda L. Parker, Tangying Lu, +14

Journal of Clinical Oncology

C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a

Nien‐Jung Chen, Christine Mirtsos, Daniel Suh, +7

Nature

InflammationInflammatory Lung DiseaseBiochemistryAllergyLung Inflammation +7