Nikolaos Zacharakis

Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer

Nikolaos Zacharakis, Harshini Chinnasamy, Mary A. Black et al. · Nature Medicine · 2018 · 757 citations

Durable Regression, Metastatic Breast Cancer, Engineering +13

Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers

Frank J. Lowery, Sri Krishna, Rami Yossef et al. · Science · 2022 · 412 citations · Full text

Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies

Devikala Gurusamy, Amanda N. Henning, Tori N. Yamamoto et al. · Cancer Cell · 2020 · 149 citations · Full text

Off-target Effect, Immunology, Gene Editing +7

A machine learning model for ranking candidate HLA class I neoantigens based on known neoepitopes from multiple human tumor types

Jared J. Gartner, Maria R. Parkhurst, Alena Gros et al. · Nature Cancer · 2021 · 79 citations · Full text

Candidate Hla Class, Tumor Heterogeneity, Medicine +9

Phenotypic signatures of circulating neoantigen-reactive CD8+ T cells in patients with metastatic cancers

Rami Yossef, Sri Krishna, Sivasish Sindiri et al. · Cancer Cell · 2023 · 69 citations · Full text

Cancer Immunosurveillance, Medicine, Immunology +9