Current Topics in Medicinal Chemistry · 2024 · 52 citations · 85 references
MedicineMedicinal ChemistryPharmacologyBiochemical PharmacologyInflammationMolecular PharmacologyAnti-inflammatory PharmacologyInflammation PharmacologyMedicinal PlantsOxidative StressOxidative Stress In InflammationPhenolic Compound AnalysisAntioxidant PharmacologyAntioxidant TreatmentOxidative Stress InflammationOxidative Stress InjuryOxidative Stress RegulationPhenolic Compound Antioxidant CapacityPhenolic Compound EffectsPlant Phenolics
P-coumaric acid is an important phenolic compound that is mainly found in fruits, vegetables, grains, and fungi and is also abundant in Chinese herbal medicines. In this review, the pharmacological research progress of p-coumaric acid in recent years was reviewed, with emphasis on its role and mechanism in oxidative stress-related diseases, such as inflammation, cardiovascular diseases, diabetes, and nervous system diseases. Studies have shown that p-coumaric acid has a positive effect on the prevention and treatment of these diseases by inhibiting oxidative stress. In addition, p-coumaric acid also has anti-tumor, antibacterial, anti-aging skin and other pharmacological effects. This review will provide reference and inspiration for further research on the pharmacological effects of p-coumaric acid.
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p-Coumaric acid kills bacteria through dual damage mechanisms
Zaixiang Lou, Hongxin Wang, Shengqi Rao et al. · Food Control · 2011 · 431 citations