Critical Reviews in Oncology/Hematology · 2023 · 13 citations · 75 references
MedicineGeneticsMolecular GeneticsCarcinogenesisMolecular OncologyOncogenesMicrorna BiologyNoncoding Rna BiologyOncogene ActivationOncogene MutationsOncogenic Signaling PathwaysRas Family OncogenesKras G12c InhibitionKras InhibitorsKras Mutation AnalysisKras Mutation TestingKras-targeted TherapyMicrorna GenesMicrorna-mediated Oncogenesis
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High Frequency of Mutations of the <i>PIK3CA</i> Gene in Human Cancers
Yardena Samuels, Zhenghe Wang, Alberto Bardelli et al. · Science · 2004 · 3.4K citations
K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
J.M. Ostrem, Ulf Peters, Martin L. Sos et al. · Nature · 2013 · 2.5K citations · Full text
The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity
Jude Canon, Karen Rex, Anne Y. Saiki et al. · Nature · 2019 · 2.3K citations
Medicine, Oncology, Pharmacology +14
Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
Jaekyoung Son, Costas A. Lyssiotis, Haoqiang Ying et al. · Nature · 2013 · 2K citations · Full text
Medicine, Cancer Biology, Oncology +12
T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer
Eric Tran, Paul F. Robbins, Yong‐Chen Lu et al. · New England Journal of Medicine · 2016 · 1.4K citations · Full text
Life Sciences, Immunology, Oncology +16