Concepedia

Modular pooled discovery of synthetic knockin sequences to program durable cell therapies

Franziska Blaeschke, Yan Yi Chen, Ryan Apathy, Bence Dániel, Andy Y. Chen, Peixin Amy Chen, Katalin Sándor, Wenxi Zhang, Zhongmei Li, Cody T. Mowery,

Cell · 2023 · 63 citations · 67 references

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67

Integrating single-cell transcriptomic data across different conditions, technologies, and species

Andrew Butler, Paul Hoffman, Peter Smibert et al. · Nature Biotechnology · 2018 · 14.7K citations · Full text

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Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection

Justin Eyquem, Jorge Mansilla‐Soto, Theodoros Giavridis et al. · Nature · 2017 · 1.8K citations · Full text

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4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors

Adrienne H. Long, Waleed Haso, Jack F. Shern et al. · Nature Medicine · 2015 · 1.8K citations · Full text

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Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia

Joseph A. Fraietta, Simon F. Lacey, Elena J. Orlando et al. · Nature Medicine · 2018 · 1.8K citations · Full text

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TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion

Omar Khan, Josephine R. Giles, Sierra J. McDonald et al. · Nature · 2019 · 1.6K citations

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