Concepedia

Elena J. Orlando

EJ

Statistics

Publications

12

Citations

3.6K

H-Index

12

Active since

2016

Affiliations

Novartis (United States)(Current)

University of Pennsylvania

Novartis (Switzerland)

Parker Institute for Cancer Immunotherapy

Children's Hospital of Philadelphia

Elena J. Orlando is an author at Novartis (United States) specializing in oncology, immunotherapy, and cancer immunology.

Publications per year

2016–2023

12

Publications

12

Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia

Joseph A. Fraietta, Simon F. Lacey, Elena J. Orlando et al. · Nature Medicine · 2018 · 1.8K citations · Full text

Life Sciences, Immunology, Oncology +16

Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell

Marco Ruella, Jun Xu, David M. Barrett et al. · Nature Medicine · 2018 · 645 citations · Full text

Life Sciences, Immunology, Oncology +12

Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia

Elena J. Orlando, Xia Han, Catherine Tribouley et al. · Nature Medicine · 2018 · 567 citations

Life Sciences, Genetics, Oncology +17

Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction

Nathan Singh, Yong Gu Lee, Olga Shestova et al. · Cancer Discovery · 2020 · 298 citations · Full text

Life Sciences, Immunology, Oncology +15

A Novel Autologous CAR-T Therapy, YTB323, with Preserved T-cell Stemness Shows Enhanced CAR T-cell Efficacy in Preclinical and Early Clinical Development

Michael Dickinson, Pere Barba, Ulrich Jäger et al. · Cancer Discovery · 2023 · 121 citations · Full text

Medicine, Hematology, Oncology +17

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