David M. Barrett

Convergence of Acquired Mutations and Alternative Splicing of <i>CD19</i> Enables Resistance to CART-19 Immunotherapy

Elena Sotillo, David M. Barrett, Kathryn L. Black et al. · Cancer Discovery · 2015 · 1.3K citations · Full text

Life Sciences, Hematology, Molecular Biology +15

Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell

Marco Ruella, Jun Xu, David M. Barrett et al. · Nature Medicine · 2018 · 645 citations · Full text

Life Sciences, Immunology, Oncology +12

Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies

Marco Ruella, David M. Barrett, Saad S. Kenderian et al. · Journal of Clinical Investigation · 2016 · 555 citations · Full text

Medicine, Hematology, Oncology +16

Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia

Joseph A. Fraietta, Kyle A. Beckwith, Prachi Patel et al. · Blood · 2016 · 461 citations · Full text

Life Sciences, Immunology, Oncology +12

Reducing <i>Ex Vivo</i> Culture Improves the Antileukemic Activity of Chimeric Antigen Receptor (CAR) T Cells

Saba Ghassemi, Selene Nuñez-Cruz, Roddy S. O’Connor et al. · Cancer Immunology Research · 2018 · 302 citations · Full text

Life Sciences, Immunology, Oncology +15