Concepedia

TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2

Chuanbin Yang, Jia Liu, Benjamin Chun‐Kit Tong, Ziying Wang, Zhou Zhu, Cheng-Fu Su, Sravan Gopalkrishnashetty Sreenivasmurthy, Jia-Xi Wu, Ashok Iyaswamy, Senthilkumar Krishnamoorthi,

Acta Pharmacologica Sinica · 2021 · 28 citations · 37 references

DOI

Concepts

References

37

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, Kotb Abdelmohsen, Akihisa Abe et al. · Autophagy · 2016 · 6K citations · Full text

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TFEB Links Autophagy to Lysosomal Biogenesis

Carmine Settembre, Chiara Di Malta, Vinicia Assunta Polito et al. · Science · 2011 · 3.3K citations

, , +17

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation

Steven A. Kliewer, James M. Lenhard, Timothy M. Willson et al. · Cell · 1995 · 2K citations · Full text

, , +16

A lysosome‐to‐nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

Carmine Settembre, Roberto Zoncu, Diego L. Medina et al. · The EMBO Journal · 2012 · 1.9K citations · Full text

, , +12

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB

Diego L. Medina, Simone Di Paola, Ivana Peluso et al. · Nature Cell Biology · 2015 · 1.4K citations

, , +12