Benjamin Chun‐Kit Tong

A small molecule transcription factor EB activator ameliorates beta‐amyloid precursor protein and Tau pathology in Alzheimer's disease models

Ju‐Xian Song, Sandeep Malampati, Yu Zeng et al. · Aging Cell · 2019 · 157 citations · Full text

Celastrol enhances transcription factor EB (TFEB)-mediated autophagy and mitigates Tau pathology: Implications for Alzheimer's disease therapy

Chuanbin Yang, Cheng-Fu Su, Ashok Iyaswamy et al. · Acta Pharmaceutica Sinica B · 2022 · 98 citations · Full text

Familial Alzheimer’s disease–associated presenilin 1 mutants promote γ-secretase cleavage of STIM1 to impair store-operated Ca ²⁺ entry

Benjamin Chun‐Kit Tong, Claire Shuk-Kwan Lee, Wing-Hei Cheng et al. · Science Signaling · 2016 · 85 citations · Full text

Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models

Ashok Iyaswamy, Xueli Wang, Senthilkumar Krishnamoorthi et al. · Redox Biology · 2022 · 66 citations · Full text

Engineering, Neurochemical Biomarkers, Amyloid Precursor Protein +24

A stress response p38 MAP kinase inhibitor SB202190 promoted TFEB/TFE3-dependent autophagy and lysosomal biogenesis independent of p38

Chuanbin Yang, Zhou Zhu, Benjamin Chun‐Kit Tong et al. · Redox Biology · 2020 · 58 citations · Full text