Concepedia

Tfeb Regulation

TFEB Regulation is a molecular signaling mechanism that controls the activity, localization, and expression of the transcription factor EB (TFEB), a master regulator of lysosomal biogenesis and autophagy, through post-translational modifications, nutrient-sensing pathways, and gene regulatory networks.

346

Publications

41.1K

Citations

2.7K

Authors

712

Institutions

Publications per year

2017–2026

269

Parents

Publications

346

TFEB Links Autophagy to Lysosomal Biogenesis

Carmine Settembre, Chiara Di Malta, Vinicia Assunta Polito et al. · Science · 2011 · 3.3K citations

, , +17

A Gene Network Regulating Lysosomal Biogenesis and Function

Marco Sardiello, Michela Palmieri, Alberto di Ronza et al. · Science · 2009 · 2.5K citations

, , +17

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB

Diego L. Medina, Simone Di Paola, Ivana Peluso et al. · Nature Cell Biology · 2015 · 1.4K citations

, , +12

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB

José A. Martina, Yong Chen, Marjan Guček et al. · Autophagy · 2012 · 1.4K citations · Full text

, , +13

The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis

Agnes Roczniak-Ferguson, Constance Petit, Florian Froehlich et al. · Science Signaling · 2012 · 1.4K citations

, , +17

1–5 of 346

Authors

2.7K

  1. AB
    Andrea Ballabio

    Telethon Institute Of Genetics And Medicine, Italy

    42 publications · 14.5K citations

    35

    h-index

  2. DL
    Diego L. Medina

    Telethon Institute Of Genetics And Medicine, Italy

    16 publications · 9.2K citations

    15

    h-index

  3. RP
    Rosa Puertollano

    National Heart Lung and Blood Institute, United States

    11 publications · 3.2K citations

    11

    h-index

  4. JA
    José A. Martina

    National Institutes of Health, United States

    10 publications · 2.9K citations

    10

    h-index

  5. GN
    Gennaro Napolitano

    Telethon Institute Of Genetics And Medicine, Italy

    9 publications · 1.5K citations

    9

    h-index

1–5 of 2.7K

Institutions

712

  1. Telethon Institute Of Genetics And Medicine

    Naples, Italy

    36 h-index

    215 publications

    97.1K citations

  2. Baylor College of Medicine

    Houston, United States

    33 h-index

    124 publications

    58.6K citations

  3. Federico II University Hospital

    Naples, Italy

    31 h-index

    65 publications

    20K citations

  4. Neurological Research Institute

    Santa Monica, United States

    31 h-index

    84 publications

    44.6K citations

  5. Texas Children's Hospital

    Houston, United States

    17 h-index

    45 publications

    33.6K citations

  6. National Institutes of Health

    Bethesda, United States

    16 h-index

    52 publications

    12.6K citations

  7. Washington University in St. Louis

    St Louis, United States

    14 h-index

    88 publications

    8.4K citations

  8. Chinese Academy of Sciences

    Beijing, China

    13 h-index

    63 publications

    3.6K citations

1–8 of 712

Venues

  1. Autophagy

    51 publications · 6.3K citations

    36

    h-index

  2. Nature Communications

    18 publications · 3.3K citations

    18

    h-index

  3. Cell Death and Disease

    12 publications · 792 citations

    12

    h-index

  4. Journal of Biological Chemistry

    JBC · 8 publications · 733 citations

    8

    h-index

  5. The EMBO Journal

    8 publications · 1.2K citations

    8

    h-index

1–5