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Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects

Emeline Dierge, Elena Debock, Céline Guilbaud, Cyril Corbet, Éric Mignolet, Louise Mignard, Estelle Bastien, Chantal Dessy, Yvan Larondelle, Olivier Féron

Cell Metabolism · 2021 · 494 citations · 22 references

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22

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

E. G. Bligh, W. J. Dyer · Canadian Journal of Biochemistry and Physiology · 1959 · 48.9K citations

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

E. G. Bligh, W. J. Dyer · Canadian Journal of Biochemistry and Physiology · 1959 · 22.9K citations

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Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

Vasanthi S. Viswanathan, Matthew J. Ryan, Harshil Dhruv et al. · Nature · 2017 · 2K citations · Full text

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Radiotherapy and Immunotherapy Promote Tumoral Lipid Oxidation and Ferroptosis via Synergistic Repression of SLC7A11

Xueting Lang, Michael D. Green, Weimin Wang et al. · Cancer Discovery · 2019 · 1.1K citations · Full text

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Lymph protects metastasizing melanoma cells from ferroptosis

Jessalyn M. Ubellacker, Alpaslan Tasdogan, Vijayashree Ramesh et al. · Nature · 2020 · 924 citations · Full text

, , +12