Vasanthi S. Viswanathan

Regulation of Ferroptotic Cancer Cell Death by GPX4

Wan Seok Yang, Rohitha Sriramaratnam, Matthew Welsch et al. · Cell · 2014 · 7.5K citations · Full text

Life Sciences, Molecular Biology, Oncology +12

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

Vasanthi S. Viswanathan, Matthew J. Ryan, Harshil Dhruv et al. · Nature · 2017 · 2K citations · Full text

Medicine, Cancer Biology, Oncology +16

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

Matthew J. Hangauer, Vasanthi S. Viswanathan, Matthew J. Ryan et al. · Nature · 2017 · 1.7K citations

Medicine, Oncology, Pharmacology +11

A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis

Yilong Zou, Michael J. Palte, Amy Deik et al. · Nature Communications · 2019 · 865 citations · Full text

Medicine, Molecular Biology, Oncology +17

Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles

John K. Eaton, Laura Furst, Richard A. Ruberto et al. · Nature Chemical Biology · 2020 · 472 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +6