John K. Eaton

Copper induces cell death by targeting lipoylated TCA cycle proteins

Peter Tsvetkov, Shannon Coy, Boryana Petrova et al. · Science · 2022 · 4.7K citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

Vasanthi S. Viswanathan, Matthew J. Ryan, Harshil Dhruv et al. · Nature · 2017 · 2K citations · Full text

Medicine, Cancer Biology, Oncology +16

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

Matthew J. Hangauer, Vasanthi S. Viswanathan, Matthew J. Ryan et al. · Nature · 2017 · 1.7K citations

Medicine, Oncology, Pharmacology +11

A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis

Yilong Zou, Michael J. Palte, Amy Deik et al. · Nature Communications · 2019 · 865 citations · Full text

Medicine, Molecular Biology, Oncology +17

Plasticity of ether lipids promotes ferroptosis susceptibility and evasion

Yilong Zou, Whitney S. Henry, Emily L. Ricq et al. · Nature · 2020 · 819 citations · Full text

Life Sciences, Biochemistry, Chemistry +13