Cyril Corbet

Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects

Emeline Dierge, Elena Debock, Céline Guilbaud et al. · Cell Metabolism · 2021 · 453 citations · Full text

Acidic Tumor Environment, Biochemistry, Omega-3 Fatty Acid +10

Acidosis Drives the Reprogramming of Fatty Acid Metabolism in Cancer Cells through Changes in Mitochondrial and Histone Acetylation

Cyril Corbet, Adán Pinto, Ruben Martherus et al. · Cell Metabolism · 2016 · 328 citations · Full text

Mitochondrial Function, Biochemistry, Metabolic Reprogramming +12

TGFβ2-induced formation of lipid droplets supports acidosis-driven EMT and the metastatic spreading of cancer cells

Cyril Corbet, Estelle Bastien, Joaquim Tiago Cardoso Leles de Jesus et al. · Nature Communications · 2020 · 299 citations · Full text

Interruption of lactate uptake by inhibiting mitochondrial pyruvate transport unravels direct antitumor and radiosensitizing effects

Cyril Corbet, Estelle Bastien, Nihed Draoui et al. · Nature Communications · 2018 · 177 citations · Full text

The SIRT1/HIF2α Axis Drives Reductive Glutamine Metabolism under Chronic Acidosis and Alters Tumor Response to Therapy

Cyril Corbet, Nihed Draoui, Florence Polet et al. · Cancer Research · 2014 · 163 citations