Nihed Draoui

Interruption of lactate uptake by inhibiting mitochondrial pyruvate transport unravels direct antitumor and radiosensitizing effects

Cyril Corbet, Estelle Bastien, Nihed Draoui et al. · Nature Communications · 2018 · 177 citations · Full text

The SIRT1/HIF2α Axis Drives Reductive Glutamine Metabolism under Chronic Acidosis and Alters Tumor Response to Therapy

Cyril Corbet, Nihed Draoui, Florence Polet et al. · Cancer Research · 2014 · 163 citations

Antitumor Activity of 7-Aminocarboxycoumarin Derivatives, a New Class of Potent Inhibitors of Lactate Influx but Not Efflux

Nihed Draoui, Olivier Schicke, Emmanuel Seront et al. · Molecular Cancer Therapeutics · 2014 · 118 citations · Full text

Antitumor Activity, Lactate Influx, Pharmacotherapy +25

Synthesis and pharmacological evaluation of carboxycoumarins as a new antitumor treatment targeting lactate transport in cancer cells

Nihed Draoui, Olivier Schicke, Antony E. Fernandes et al. · Bioorganic & Medicinal Chemistry · 2013 · 68 citations · Full text

Drug Targeting, Medicine, Pharmacology +10

Vitamin E-based micelles enhance the anticancer activity of doxorubicin

Fabienne Danhier, Trésor Touan Bi Kouhé, Nicolas Duhem et al. · International Journal of Pharmaceutics · 2014 · 37 citations

Nanomedicine, Medicinal Chemistry, Polymer-drug Conjugate +3