Concepedia

Correction of X-CGD patient HSPCs by targeted CYBB cDNA insertion using CRISPR/Cas9 with 53BP1 inhibition for enhanced homology-directed repair

Colin L. Sweeney, Mara Pavel-Dinu, Uimook Choi, Julie Brault, Taylor Liu, Sherry Koontz, Linhong Li, Narda Theobald, Janet S. Lee, Ezekiel Bello,

Gene Therapy · 2021 · 52 citations · 69 references

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References

69

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text

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Multiplex Genome Engineering Using CRISPR/Cas Systems

Le Cong, F. Ann Ran, David Cox et al. · Science · 2013 · 15.7K citations

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RNA-Guided Human Genome Engineering via Cas9

Prashant Mali, Luhan Yang, Kevin M. Esvelt et al. · Science · 2013 · 9.4K citations · Full text

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A TALE nuclease architecture for efficient genome editing

Jeffrey C. Miller, Siyuan Tan, Guijuan Qiao et al. · Nature Biotechnology · 2010 · 2.1K citations

, , +14

Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells

Van Trung Chu, Timm Weber, Benedikt Wefers et al. · Nature Biotechnology · 2015 · 1.2K citations

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