Benedikt Wefers

Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells

Van Trung Chu, Timm Weber, Benedikt Wefers et al. · Nature Biotechnology · 2015 · 1.2K citations

Life Sciences, Genetics, Molecular Biology +14

The FTD‐like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism

Gernot Kleinberger, Matthias Brendel, Éva Mracskó et al. · The EMBO Journal · 2017 · 286 citations

Life Sciences, Neurobiology, Neuroscience +16

The Trem2 R47H Alzheimer’s risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans

Xianyuan Xiang, Thomas M. Piers, Benedikt Wefers et al. · Molecular Neurodegeneration · 2018 · 206 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides

Benedikt Wefers, Mélanie Meyer, Oskar Ortiz et al. · Proceedings of the National Academy of Sciences · 2013 · 145 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Generating Conditional Knockout Mice

Roland H. Friedel, Wolfgang Wurst, Benedikt Wefers et al. · Methods in molecular biology · 2010 · 92 citations

Veterinary Medicine, Genetics, Molecular Genetics +8