Thomas M. Piers

Microtubule-associated protein tau is essential for long-term depression in the hippocampus

Tetsuya Kimura, Daniel J. Whitcomb, Jihoon Jo et al. · Philosophical Transactions of the Royal Society B Biological Sciences · 2013 · 288 citations · Full text

Synaptic Transmission, Long-term Depression, Neurochemical Biomarkers +17

<i>Trem2</i> promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions

Wenfei Liu, Orjona Taso, Rui Wang et al. · Human Molecular Genetics · 2020 · 201 citations · Full text

Tau Phosphorylation at Serine 396 Residue Is Required for Hippocampal LTD

Philip Regan, Thomas M. Piers, Jee Hyun Yi et al. · Journal of Neuroscience · 2015 · 187 citations · Full text

Synaptic Transmission, Tau Ko Mice, Molecular Biology +19

The Trem2 R47H Alzheimer’s risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans

Xianyuan Xiang, Thomas M. Piers, Benedikt Wefers et al. · Molecular Neurodegeneration · 2018 · 173 citations · Full text

Human Induced Pluripotent Stem Cell-Derived Microglia-Like Cells Harboring TREM2 Missense Mutations Show Specific Deficits in Phagocytosis

Pablo Garcia-Reitboeck, Alexandra Phillips, Thomas M. Piers et al. · Cell Reports · 2018 · 163 citations · Full text