Concepedia
CNS Neuroscience & Therapeutics · 2021 · 33 citations · 32 references
Open access
Our results indicate that the noncompetitive AMPAR antagonist perampanel protects the NVU system and reduces brain damage after TBI via activating the Sirt3 cascades.
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Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation
Xiaolei Qiu, Katharine Brown, Matthew D. Hirschey et al. · Cell Metabolism · 2010 · 1.3K citations · Full text
Caloric Restriction, Biochemistry, Lipid Peroxidation +6
Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation
David B. Lombard, Frederick W. Alt, Hwei-Ling Cheng et al. · Molecular and Cellular Biology · 2007 · 1.2K citations · Full text
Lifespan Extension, Systems Biology, Soluble Mitochondrial Protein +10
SIRT3 Protein Deacetylates Isocitrate Dehydrogenase 2 (IDH2) and Regulates Mitochondrial Redox Status
Wei Yu, Kristin E. Dittenhafer‐Reed, John M. Denu · Journal of Biological Chemistry · 2012 · 432 citations · Full text
Exogenous NAD Blocks Cardiac Hypertrophic Response via Activation of the SIRT3-LKB1-AMP-activated Kinase Pathway
Vinodkumar B. Pillai, Nagalingam R. Sundaresan, Gene Kim et al. · Journal of Biological Chemistry · 2009 · 422 citations · Full text
Perampanel: A novel, orally active, noncompetitive AMPA-receptor antagonist that reduces seizure activity in rodent models of epilepsy
Takahisa Hanada, Yutaka Hashizume, Naoki Tokuhara et al. · Epilepsia · 2011 · 396 citations · Full text