Takahisa Hanada

Perampanel: A novel, orally active, noncompetitive AMPA-receptor antagonist that reduces seizure activity in rodent models of epilepsy

Takahisa Hanada, Yutaka Hashizume, Naoki Tokuhara et al. · Epilepsia · 2011 · 396 citations · Full text

Discovery of 2-(2-Oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl)benzonitrile (Perampanel): A Novel, Noncompetitive α-Amino-3-hydroxy-5-methyl-4-isoxazolepropanoic Acid (AMPA) Receptor Antagonist

Shigeki Hibi, Koshi Ueno, Satoshi Nagato et al. · Journal of Medicinal Chemistry · 2012 · 177 citations

Synaptic Transmission, Pyridone Ring, Neurotransmitter +21

Ultra-high-dose methylcobalamin in amyotrophic lateral sclerosis: a long-term phase II/III randomised controlled study

Ryuji Kaji, Takashi Imai, Yasuo Iwasaki et al. · Journal of Neurology Neurosurgery & Psychiatry · 2019 · 76 citations · Full text

Involvement of P-type calcium channels in high potassium-elicited release of neurotransmitters from rat brain slices

M. Kimura, Yoshinori Yamanishi, Takahisa Hanada et al. · Neuroscience · 1995 · 58 citations

Neurophysiology, High Potassium-elicited Release, Synaptic Transmission +13

Effect of perampanel, a novel AMPA antagonist, on benzodiazepine‐resistant status epilepticus in a lithium‐pilocarpine rat model

Takahisa Hanada, Katsutoshi Ido, Takashi Kosasa · Pharmacology Research & Perspectives · 2014 · 58 citations · Full text

Psychotropic Medication, Receptor Antagonists, Pharmacotherapy +17