Shigeki Hibi

Discovery of 2-(2-Oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl)benzonitrile (Perampanel): A Novel, Noncompetitive α-Amino-3-hydroxy-5-methyl-4-isoxazolepropanoic Acid (AMPA) Receptor Antagonist

Shigeki Hibi, Koshi Ueno, Satoshi Nagato et al. · Journal of Medicinal Chemistry · 2012 · 181 citations

Medicine, Neuroscience, Pharmacology +16

A Novel Type of Retinoic Acid Receptor Antagonist: Synthesis and Structure-Activity Relationships of Heterocyclic Ring-Containing Benzoic Acid Derivatives

Shigeki Hibi, K. Kikuchi, Shinya Abe et al. · Journal of Medicinal Chemistry · 1995 · 45 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Syntheses and Structure−Activity Relationships of 5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-quinoxaline Derivatives with Retinoic Acid Receptor α Agonistic Activity

K. Kikuchi, Shigeki Hibi, Hiroyuki Yoshimura et al. · Journal of Medicinal Chemistry · 2000 · 44 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Synthesis and Structure–Activity Relationships of Pyrazolo[1,5-<i>a</i>]pyridine Derivatives: Potent and Orally Active Antagonists of Corticotropin-Releasing Factor 1 Receptor

Y. Takahashi, Shigeki Hibi, Yorihisa Hoshino et al. · Journal of Medicinal Chemistry · 2012 · 35 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Novel Dual Inhibitors of 5-Lipoxygenase and Thromboxane A2 Synthetase: Synthesis and Structure-Activity Relationships of 3-Pyridylmethyl-Substituted 2-Amino-6-hydroxybenzothiazole Derivatives

Shigeki Hibi, Yasushi Okamoto, Katsuya Tagami et al. · Journal of Medicinal Chemistry · 1994 · 34 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8