David B. Lombard

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

Matthew D. Hirschey, Tadahiro Shimazu, Eric S. Goetzman et al. · Nature · 2010 · 1.6K citations · Full text

Mitochondrial Function, Biochemistry, Mitochondrial Fatty-acid Oxidation +4

Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6

Raúl Mostoslavsky, Katrin F. Chua, David B. Lombard et al. · Cell · 2006 · 1.6K citations · Full text

Lifespan Extension, Chromatin, Genome Instability +10

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

In Hye Lee, Liu Cao, Raúl Mostoslavsky et al. · Proceedings of the National Academy of Sciences · 2008 · 1.4K citations · Full text

Cell Autophagy, Mitophagy, Signal Transduction +15

Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation

David B. Lombard, Frederick W. Alt, Hwei-Ling Cheng et al. · Molecular and Cellular Biology · 2007 · 1.2K citations · Full text

Lifespan Extension, Systems Biology, Soluble Mitochondrial Protein +10

SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways

Jeong-Soon Park, Yue Chen, Daniel X. Tishkoff et al. · Molecular Cell · 2013 · 997 citations · Full text

Biochemistry, Metabolic Regulation, Metabolic Profiling +2