Hwei-Ling Cheng

Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6

Raúl Mostoslavsky, Katrin F. Chua, David B. Lombard et al. · Cell · 2006 · 1.6K citations · Full text

Lifespan Extension, Chromatin, Genome Instability +10

Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation

David B. Lombard, Frederick W. Alt, Hwei-Ling Cheng et al. · Molecular and Cellular Biology · 2007 · 1.2K citations · Full text

Lifespan Extension, Systems Biology, Soluble Mitochondrial Protein +10

Late embryonic lethality and impaired V (D)J recombination in mice lacking DNA ligase IV

Karen M. Frank, JoAnn Sekiguchi, Katherine J. Seidl et al. · Nature · 1998 · 583 citations

Knockout Mouse, Genome Instability, Developmental Biology +9

Tissue-specific regulation of SIRT1 by calorie restriction

Danica Chen, Joanne Bruno, Erin Easlon et al. · Genes & Development · 2008 · 552 citations · Full text

Immunology, Caloric Restriction, Oxidative Stress +16

Mice Lacking Histone Deacetylase 6 Have Hyperacetylated Tubulin but Are Viable and Develop Normally

Yu Zhang, So-Hee Kwon, Teppei Yamaguchi et al. · Molecular and Cellular Biology · 2008 · 548 citations · Full text