John M. Denu

The Human Sir2 Ortholog, SIRT2, Is an NAD+-Dependent Tubulin Deacetylase

Brian J. North, Brett Marshall, Margie T. Borra et al. · Molecular Cell · 2003 · 1.5K citations · Full text

Life Sciences, Genetics, Molecular Biology +9

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction

Shinichi Someya, Wei Yu, William C. Hallows et al. · Cell · 2010 · 1.1K citations · Full text

Health Professions, Audiology, Nutritional Sciences +11

Mechanism of Human SIRT1 Activation by Resveratrol

Margie T. Borra, Brian C. Smith, John M. Denu · Journal of Biological Chemistry · 2005 · 1.1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Specific and Reversible Inactivation of Protein Tyrosine Phosphatases by Hydrogen Peroxide:  Evidence for a Sulfenic Acid Intermediate and Implications for Redox Regulation

John M. Denu, Kirk Tanner · Biochemistry · 1998 · 941 citations

Life Sciences, Biochemistry, Molecular Biology +16

Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

William C. Hallows, Susan Lee, John M. Denu · Proceedings of the National Academy of Sciences · 2006 · 794 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12