Concepedia

Management of Gout-associated MSU crystals-induced NLRP3 inflammasome activation by procyanidin B2: targeting IL-1β and Cathepsin B in macrophages

Chun‐Ying Qiao, Ying Li, Yue Shang, Min Jiang, Jian Liu, Zi‐Ying Zhan, Huan Ye, Yong-Ce Lin, Jing-Ya Jiao, Rong-Hui Sun,

Inflammopharmacology · 2020 · 39 citations · 25 references

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25

Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome

Takuma Misawa, Michihiro Takahama, Tatsuya Kozaki et al. · Nature Immunology · 2013 · 848 citations

, , +16

Anthrax lethal toxin and <i>Salmonella</i> elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms

Susan L. Fink, Tessa Bergsbaken, Brad T. Cookson · Proceedings of the National Academy of Sciences · 2008 · 407 citations · Full text

, , +17

β-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares

Emily L. Goldberg, Jennifer L. Asher, Ryan D. Molony et al. · Cell Reports · 2017 · 362 citations · Full text

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Cathepsin B Is Required for NLRP3 Inflammasome Activation in Macrophages, Through NLRP3 Interaction

Angélique Chevriaux, Thomas Pilot, Valentin Dérangère et al. · Frontiers in Cell and Developmental Biology · 2020 · 192 citations · Full text

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NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of acute arthritis

Carlo Marchetti, Benjamin J. Swartzwelter, Marije I. Koenders et al. · Arthritis Research & Therapy · 2018 · 161 citations · Full text

, , +17