Valentin Dérangère

Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

Mélanie Bruchard, Grégoire Mignot, Valentin Dérangère et al. · Nature Medicine · 2012 · 763 citations

Inflammation, Tumor Biology, Cancer Immunosurveillance +8

The receptor NLRP3 is a transcriptional regulator of TH2 differentiation

Mélanie Bruchard, Cédric Rébé, Valentin Dérangère et al. · Nature Immunology · 2015 · 396 citations

Transcriptional Regulation, Signal Transduction, Signaling Pathway +8

Lysophosphatidylcholine acyltransferase 2-mediated lipid droplet production supports colorectal cancer chemoresistance

Alexia K. Cotte, Virginie Aires, Maxime Fredon et al. · Nature Communications · 2018 · 338 citations · Full text

Stat3 and Gfi-1 Transcription Factors Control Th17 Cell Immunosuppressive Activity via the Regulation of Ectonucleotidase Expression

Fanny Chalmin, Grégoire Mignot, Mélanie Bruchard et al. · Immunity · 2012 · 322 citations · Full text

Inflammation, Ectonucleotidase Expression, Transcriptional Regulation +9

Accumulation of MDSC and Th17 Cells in Patients with Metastatic Colorectal Cancer Predicts the Efficacy of a FOLFOX–Bevacizumab Drug Treatment Regimen

Emeric Limagne, Romain Euvrard, Marion Thibaudin et al. · Cancer Research · 2016 · 256 citations