Mélanie Bruchard

5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell–Dependent Antitumor Immunity

Julie Vincent, Grégoire Mignot, Fanny Chalmin et al. · Cancer Research · 2010 · 1.2K citations

Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells

Fanny Chalmin, Sylvain Ladoire, Grégoire Mignot et al. · Journal of Clinical Investigation · 2010 · 978 citations · Full text

Human Mdscs, Immunology, Extracellular Microvesicles +16

Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

Mélanie Bruchard, Grégoire Mignot, Valentin Dérangère et al. · Nature Medicine · 2012 · 763 citations

Inflammation, Tumor Biology, Cancer Immunosurveillance +8

IL-1β, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs

Suzanne M. Bal, Jochem H. Bernink, Maho Nagasawa et al. · Nature Immunology · 2016 · 438 citations

Inflammatory Lung Disease, Lung Inflammation, Innate Lymphoid Cells +17

The receptor NLRP3 is a transcriptional regulator of TH2 differentiation

Mélanie Bruchard, Cédric Rébé, Valentin Dérangère et al. · Nature Immunology · 2015 · 396 citations

Transcriptional Regulation, Signal Transduction, Signaling Pathway +8