Mélanie Bruchard

5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell–Dependent Antitumor Immunity

Julie Vincent, Grégoire Mignot, Fanny Chalmin et al. · Cancer Research · 2010 · 1.2K citations

Medicine, Immunology, Oncology +17

Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells

Fanny Chalmin, Sylvain Ladoire, Grégoire Mignot et al. · Journal of Clinical Investigation · 2010 · 987 citations · Full text

Medicine, Immunology, Oncology +16

Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

Mélanie Bruchard, Grégoire Mignot, Valentin Dérangère et al. · Nature Medicine · 2012 · 773 citations

Medicine, Cancer Biology, Oncology +16

IL-1β, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs

Suzanne M. Bal, Jochem H. Bernink, Maho Nagasawa et al. · Nature Immunology · 2016 · 453 citations · Full text

Life Sciences, Cell Biology, Immunology +16

The receptor NLRP3 is a transcriptional regulator of TH2 differentiation

Mélanie Bruchard, Cédric Rébé, Valentin Dérangère et al. · Nature Immunology · 2015 · 397 citations

Life Sciences, Immunology, Molecular Biology +16