Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

John G. Doench, Nicolò Fusi, Meagan E. Sullender et al. · Nature Biotechnology · 2016 · 5K citations

Life Sciences, Biotechnology, Molecular Biology +13

Essentials of glycobiology

G. Ya. Wiederschain · Biochemistry (Moscow) · 2009 · 4.1K citations · Full text

Human Keratinocytes That Express hTERT and Also Bypass a p16^INK4a-Enforced Mechanism That Limits Life Span Become Immortal yet Retain Normal Growth and Differentiation Characteristics

Mark A. Dickson, William C. Hahn, Yasushi Ino et al. · Molecular and Cellular Biology · 2000 · 1.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

Symbol Nomenclature for Graphical Representations of Glycans

Ajit Varki, Richard D. Cummings, Markus Aebi et al. · Glycobiology · 2015 · 1.1K citations · Full text

Life Sciences, Anatomy, Bioinformatics +15