Specific Genetic Predictors of Chemotherapeutic Response and Survival in Patients With Anaplastic Oligodendrogliomas

J. Gregory Cairncross, Keisuke Ueki, Magdelena C. Zlatescu, +9

JNCI Journal of the National Cancer Institute

Anaplastic OligodendrogliomasPathologyHigh-grade GliomasGliomaTumor Biology +18

Human Keratinocytes That Express hTERT and Also Bypass a p16^INK4a-Enforced Mechanism That Limits Life Span Become Immortal yet Retain Normal Growth and Differentiation Characteristics

Mark A. Dickson, William C. Hahn, Yasushi Ino, +6

Molecular and Cellular Biology

Retain Normal GrowthTelomerase ExpressionSkin DevelopmentDevelopmental BiologyCell Regulation +11

Autocrine TGF-β Signaling Maintains Tumorigenicity of Glioma-Initiating Cells through Sry-Related HMG-Box Factors

Hiroaki Ikushima, Tomoki Todo, Yasushi Ino, +3

Cell stem cell

Glioma-initiating CellsSry-related Hmg-box FactorsSignaling PathwayGliomaMedicine +7

Cyclic RGD-Linked Polymeric Micelles for Targeted Delivery of Platinum Anticancer Drugs to Glioblastoma through the Blood–Brain Tumor Barrier

Yutaka Miura, Tomoya Takenaka, Kazuko Toh, +10

ACS Nano

Crgd-linked Polymeric MicellesNanotherapeuticsEngineeringTargeted DeliveryPeptide Science +20

Intratumoral oncolytic herpes virus G47∆ for residual or recurrent glioblastoma: a phase 2 trial

Tomoki Todo, Hirotaka Ito, Yasushi Ino, +4

Nature Medicine

Molecular subtypes of anaplastic oligodendroglioma: implications for patient management at diagnosis.

Yasushi Ino, Rebecca A. Betensky, Magdalena C. Ƶlatescu, +6

PubMed

Malignant Transformation of Neurofibromas in Neurofibromatosis 1 Is Associated with CDKN2A/p16 Inactivation

G. Petur Nielsen, Anat Stemmer‐Rachamimov, Yasushi Ino, +3

American Journal Of Pathology

Neuro-oncologyCdkn2a/p16 InactivationFibrosisTumoral PathologyPerineural Invasion +9

Allelic loss of chromosome 1p and radiotherapy plus chemotherapy in patients with oligodendrogliomas

Glenn Bauman, Yasushi Ino, Keisuke Ueki, +6

International Journal of Radiation Oncology*Biology*Physics

Neuro-oncologyTumor BiologyAllelic LossTumoral PathologyMedicine +8

A phase I/II study of triple-mutated oncolytic herpes virus G47∆ in patients with progressive glioblastoma

Tomoki Todo, Yasushi Ino, Hiroshi Ohtsu, +2

Nature Communications

PTEN Is a Target of Chromosome 10q Loss in Anaplastic Oligodendrogliomas and PTEN Alterations Are Associated with Poor Prognosis

Hikaru Sasaki, Magdalena C. Ƶlatescu, Rebecca A. Betensky, +3

American Journal Of Pathology

Anaplastic OligodendrogliomasChromosome 10QPathologyPoor PrognosisRadiation Oncology +3