Selective sensitivity of EZH2 inhibitors based on synthetic lethality in ARID1A-deficient gastric cancer

Comprehensive molecular characterization of gastric adenocarcinoma

Adam J. Bass, Vésteinn Thórsson, David Van Den Berg et al. · Nature · 2014 · 6.5K citations · Full text

Medicine, Molecular Biology, Oncology +17

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

Michael T. McCabe, Heidi M. Ott, Gopinath Ganji et al. · Nature · 2012 · 1.8K citations

Medicine, Molecular Genetics, Oncology +15

Comprehensive molecular characterization of clinical responses to PD-1 inhibition in metastatic gastric cancer

Seung Tae Kim, Răzvan Cristescu, Adam J. Bass et al. · Nature Medicine · 2018 · 1.7K citations

Medicine, Cancer Biology, Oncology +17

Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer

Kai Wang, Junsuo Kan, Siu Tsan Yuen et al. · Nature Genetics · 2011 · 775 citations

Medicine, Genetics, Molecular Genetics +16

A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells

Sarah K. Knutson, Tim J. Wigle, Natalie M. Warholic et al. · Nature Chemical Biology · 2012 · 761 citations

Medicine, Molecular Biology, Oncology +12