Gopinath Ganji

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

Michael T. McCabe, Heidi M. Ott, Gopinath Ganji et al. · Nature · 2012 · 1.8K citations

Medicine, Molecular Genetics, Oncology +15

Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)

Michael T. McCabe, Alan P. Graves, Gopinath Ganji et al. · Proceedings of the National Academy of Sciences · 2012 · 485 citations · Full text

Life Sciences, Genetics, Oncology +17

BET Inhibition Silences Expression of MYCN and BCL2 and Induces Cytotoxicity in Neuroblastoma Tumor Models

Anastasia Wyce, Gopinath Ganji, Kimberly N. Smitheman et al. · PLoS ONE · 2013 · 204 citations · Full text

Medicine, Molecular Biology, Oncology +17

Response to ERBB3-Directed Targeted Therapy in <i>NRG1</i> -Rearranged Cancers

Alexander Drilon, Romel Somwar, Biju Mangatt et al. · Cancer Discovery · 2018 · 204 citations · Full text

Medicine, Cancer Biology, Oncology +16

A First-Time-in-Human Study of GSK2636771, a Phosphoinositide 3 Kinase Beta-Selective Inhibitor, in Patients with Advanced Solid Tumors

Joaquı́n Mateo, Gopinath Ganji, Charlotte Lemech et al. · Clinical Cancer Research · 2017 · 143 citations · Full text

Medicine, Oncology, Pharmacology +17