Michael T. McCabe

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

Michael T. McCabe, Heidi M. Ott, Gopinath Ganji et al. · Nature · 2012 · 1.8K citations

Medicine, Molecular Genetics, Oncology +15

EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation

Wendy Béguelin, Relja Popovic, Matt Teater et al. · Cancer Cell · 2013 · 841 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer

Marian L. Burr, Christina E. Sparbier, Kah Lok Chan et al. · Cancer Cell · 2019 · 642 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Reductive carboxylation supports redox homeostasis during anchorage-independent growth

Lei Jiang, Alexander A. Shestov, Pamela Swain et al. · Nature · 2016 · 595 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Natural Mutagenesis of Human Genomes by Endogenous Retrotransposons

Rebecca C. Iskow, Michael T. McCabe, Ryan E. Mills et al. · Cell · 2010 · 560 citations

Life Sciences, Genetics, Molecular Genetics +11