Alexander A. Shestov

Reductive carboxylation supports redox homeostasis during anchorage-independent growth

Lei Jiang, Alexander A. Shestov, Pamela Swain et al. · Nature · 2016 · 582 citations · Full text

Redox Regulator, Anchorage-independent Growth, Cell Growth +4

Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step

Alexander A. Shestov, Xiaojing Liu, Zheng Ser et al. · eLife · 2014 · 301 citations · Full text

Limiting Step, Upper Glycolysis, Glycobiology +19

A Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural Product

Maria V. Liberti, Ziwei Dai, Suzanne E. Wardell et al. · Cell Metabolism · 2017 · 196 citations · Full text

Medicinal Chemistry, Drug Target, Drug Targeting +11

Inhibition of Mitochondrial Complex II by the Anticancer Agent Lonidamine

Lili Guo, Alexander A. Shestov, Andrew J. Worth et al. · Journal of Biological Chemistry · 2015 · 173 citations · Full text

Characterization of the Usage of the Serine Metabolic Network in Human Cancer

Mahya Mehrmohamadi, Xiaojing Liu, Alexander A. Shestov et al. · Cell Reports · 2014 · 167 citations · Full text