Concepedia

A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells

Sarah K. Knutson, Tim J. Wigle, Natalie M. Warholic, Christopher J. Sneeringer, Christina J. Allain, Christine R. Klaus, Joelle D. Sacks, Alejandra Raimondi, Christina R. Majer, Jeffrey Song,

Nature Chemical Biology · 2012 · 761 citations · 42 references

DOI

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References

42

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

Paul B. Chapman, Axel Hauschild, Caroline Robert et al. · New England Journal of Medicine · 2011 · 7.7K citations · Full text

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Anaplastic Lymphoma Kinase Inhibition in Non–Small-Cell Lung Cancer

Eunice L. Kwak, Yung‐Jue Bang, D. Ross Camidge et al. · New England Journal of Medicine · 2010 · 4.5K citations

, , +14

Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing

Ru Cao, Liangjun Wang, Hengbin Wang et al. · Science · 2002 · 3.8K citations

, , +16

The polycomb group protein EZH2 is involved in progression of prostate cancer

Sooryanarayana Varambally, Saravana M. Dhanasekaran, Ming Zhou et al. · Nature · 2002 · 2.7K citations · Full text

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An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

Ittai Ben‐Porath, Matthew Thomson, Vincent J. Carey et al. · Nature Genetics · 2008 · 2.6K citations · Full text

, , +16