Concepedia

Chronic cerebral hypoperfusion activates AIM2 and NLRP3 inflammasome

Hirofumi Matsuyama, Akihiro Shindo, Takuya Shimada, Kenichiro Yata, Hideaki Wakita, Ryōsuke Takahashi, Hidekazu Tomimoto

Brain Research · 2020 · 50 citations · 18 references

DOI

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18

The Inflammasome

Fabio Martinon, Kimberly Burns, Jürg Tschopp · Molecular Cell · 2002 · 6K citations · Full text

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

Michael T. Heneka, Markus P. Kummer, Andrea Stutz et al. · Nature · 2012 · 2.9K citations · Full text

, , +14

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

Rebecca C. Coll, Avril A. B. Robertson, Jae Jin Chae et al. · Nature Medicine · 2015 · 2.8K citations · Full text

, , +15

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

Xiaoming Hu, Peiying Li, Yanling Guo et al. · Stroke · 2012 · 1.6K citations · Full text

, , +17

White Matter Lesions and Glial Activation in a Novel Mouse Model of Chronic Cerebral Hypoperfusion

Masunari Shibata, Ryo Ohtani, Masafumi Ihara et al. · Stroke · 2004 · 578 citations · Full text

, , +17