Concepedia

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

Michael T. Heneka, Markus P. Kummer, Andrea Stutz, Andrea Delekate, Stephanie Schwartz, Ana Vieira‐Saecker, Angelika Griep, Daisy Axt, Anita Remus, Te‐Chen Tzeng,

Nature · 2012 · 2.9K citations · 26 references

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26

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

Annett Halle, Veit Hornung, Gabor C. Petzold et al. · Nature Immunology · 2008 · 2.4K citations · Full text

, , +13

Decreased Clearance of CNS β-Amyloid in Alzheimer’s Disease

Kwasi G. Mawuenyega, Wendy Sigurdson, Vitaliy Ovod et al. · Science · 2010 · 2.1K citations · Full text

, , +13

Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock

Ping Li, Hamish Allen, Subhashis Banerjee et al. · Cell · 1995 · 1.4K citations · Full text

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Microglial Dysfunction and Defective β-Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice

Suzanne E. Hickman, Elizabeth Allison, Joseph El Khoury · Journal of Neuroscience · 2008 · 1.3K citations · Full text

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Object recognition in rats and mice: a one-trial non-matching-to-sample learning task to study 'recognition memory'

Rick A. Bevins, Joyce Besheer · Nature Protocols · 2006 · 1.3K citations

, , +16