Michael T. Heneka

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

Michael T. Heneka, Markus P. Kummer, Andrea Stutz et al. · Nature · 2012 · 2.8K citations · Full text

App/ps1 Mice, Neurodegenerative Diseases, Signal Transduction +11

NLRP3 inflammasome activation drives tau pathology

Christina Ising, Carmen Venegas, Shuangshuang Zhang et al. · Nature · 2019 · 1.4K citations · Full text

Inflammation, Autoimmune Disease, Disease Mechanism +8

Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease

Carmen Venegas, Sathish Kumar, Bernardo S. Franklin et al. · Nature · 2017 · 950 citations

Microglia-derived Asc, Neurodegenerative Diseases, Alzheimer's Disease +7

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis

Gernot Kleinberger, Yoshinori Yamanishi, Marc Suárez‐Calvet et al. · Science Translational Medicine · 2014 · 805 citations

A guiding map for inflammation

Mihai G. Netea, Frances R. Balkwill, Michel Chonchol et al. · Nature Immunology · 2017 · 794 citations · Full text

Inflammation, Anti-inflammatory, Autoimmune Disease +7