Concepedia

NLRP3 inflammasome activation drives tau pathology

Christina Ising, Carmen Venegas, Shuangshuang Zhang, Hannah Scheiblich, Susanne V. Schmidt, Ana Vieira‐Saecker, Stephanie Schwartz, Shadi Albasset, Róisín M. McManus, Darío Tejera,

Nature · 2019 · 1.5K citations · 23 references

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23

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

Damian Szklarczyk, John H. Morris, Helen Cook et al. · Nucleic Acids Research · 2016 · 7.4K citations · Full text

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NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

Michael T. Heneka, Markus P. Kummer, Andrea Stutz et al. · Nature · 2012 · 2.9K citations · Full text

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The NALP3 inflammasome is involved in the innate immune response to amyloid-β

Annett Halle, Veit Hornung, Gabor C. Petzold et al. · Nature Immunology · 2008 · 2.4K citations · Full text

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Depletion of microglia and inhibition of exosome synthesis halt tau propagation

Hirohide Asai, Seiko Ikezu, Satoshi Tsunoda et al. · Nature Neuroscience · 2015 · 1.6K citations

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Formation of Neurofibrillary Tangles in P301L Tau Transgenic Mice Induced by Aβ42 Fibrils

Jürgen Götz, F. Chen, Jo Van Dorpe et al. · Science · 2001 · 1.5K citations

, , +14