Róisín M. McManus

NLRP3 inflammasome activation drives tau pathology

Christina Ising, Carmen Venegas, Shuangshuang Zhang et al. · Nature · 2019 · 1.4K citations · Full text

Inflammation, Autoimmune Disease, Disease Mechanism +8

IFN-γ Production by Amyloid β–Specific Th1 Cells Promotes Microglial Activation and Increases Plaque Burden in a Mouse Model of Alzheimer’s Disease

Tara C. Browne, Keith McQuillan, Róisín M. McManus et al. · The Journal of Immunology · 2013 · 310 citations

Increases Plaque Burden, Immunology, Immune Regulation +24

Soluble Aβ oligomers and protofibrils induce NLRP3 inflammasome activation in microglia

Asta Lučiūnaitė, Róisín M. McManus, Marija Jankunec et al. · Journal of Neurochemistry · 2019 · 172 citations · Full text

Lung CD4 Tissue-Resident Memory T Cells Mediate Adaptive Immunity Induced by Previous Infection of Mice with <i>Bordetella pertussis</i>

Mieszko M. Wilk, Alicja Misiak, Róisín M. McManus et al. · The Journal of Immunology · 2017 · 149 citations

Respiratory infection promotes T cell infiltration and amyloid-β deposition in APP/PS1 mice

Róisín M. McManus, Sarah Higgins, Kingston H. G. Mills et al. · Neurobiology of Aging · 2013 · 131 citations

App/ps1 Mice, Inflammatory Lung Disease, Lung Inflammation +11