Concepedia

R117H-CFTR function and response to VX-770 correlate with mRNA and protein expression in intestinal organoids

Peter van Mourik, P. Van Haaren, Evelien Kruisselbrink, Cemil Korkmaz, Hettie M. Janssens, Karin M. de Winter‐de Groot, Cornelis K. van der Ent, Marne C. Hagemeijer, Jeffrey M. Beekman

Journal of Cystic Fibrosis · 2020 · 14 citations · 20 references

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References

20

A functional CFTR assay using primary cystic fibrosis intestinal organoids

Johanna F. Dekkers, Caroline L. Wiegerinck, Hugo R. de Jonge et al. · Nature Medicine · 2013 · 997 citations

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Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis

Johanna F. Dekkers, Gitte Berkers, Evelien Kruisselbrink et al. · Science Translational Medicine · 2016 · 549 citations

, , +8

Genetic basis of variable exon 9 skipping in cystic fibrosis transmembrane conductance regulator mRNA

Chin-Shyan Chu, Bruce C. Trapnell, S M Curristin et al. · Nature Genetics · 1993 · 518 citations

, , +13

A mutation in CFTR produces different phenotypes depending on chromosomal background

Sandra Kiesewetter, Milan Maçek, Claire Davis et al. · Nature Genetics · 1993 · 442 citations

, , +12

Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis

Gitte Berkers, Peter van Mourik, Annelotte M. Vonk et al. · Cell Reports · 2019 · 310 citations · Full text

, , +16