Gitte Berkers

Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis

Johanna F. Dekkers, Gitte Berkers, Evelien Kruisselbrink et al. · Science Translational Medicine · 2016 · 549 citations

Medicine, Pharmacology, Clinical Pharmacology +8

Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis

Gitte Berkers, Peter van Mourik, Annelotte M. Vonk et al. · Cell Reports · 2019 · 310 citations · Full text

Medicine, Cell Biology, Pharmacology +16

CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank

Maarten H. Geurts, Eyleen de Poel, Gimano D. Amatngalim et al. · Cell stem cell · 2020 · 220 citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

Stratifying infants with cystic fibrosis for disease severity using intestinal organoid swelling as a biomarker of CFTR function

Karin M. de Winter-de Groot, Hettie M. Janssens, Rick T. van Uum et al. · European Respiratory Journal · 2018 · 78 citations · Full text

Medicine, Pediatrics, Physiology +16

Forskolin-induced swelling of intestinal organoids correlates with disease severity in adults with cystic fibrosis and homozygous F508del mutations

Karin M. de Winter – de Groot, Gitte Berkers, Rozemarijn E.P. Marck – van der Wilt et al. · Journal of Cystic Fibrosis · 2019 · 59 citations

Medicine, Genetics, Molecular Genetics +12