Eyleen de Poel

CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank

Maarten H. Geurts, Eyleen de Poel, Gimano D. Amatngalim et al. · Cell stem cell · 2020 · 220 citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

Evaluating CRISPR-based prime editing for cancer modeling and CFTR repair in organoids

Maarten H. Geurts, Eyleen de Poel, Cayetano Pleguezuelos‐Manzano et al. · Life Science Alliance · 2021 · 139 citations · Full text

Life Sciences, Biotechnology, Genetics +16

Comparison of ex vivo and in vitro intestinal cystic fibrosis models to measure CFTR-dependent ion channel activity

Domenique D. Zomer-van Ommen, Eyleen de Poel, Evelien Kruisselbrink et al. · Journal of Cystic Fibrosis · 2018 · 55 citations

Natural Sciences, Biophysics, Physiology +16

FDA-approved drug screening in patient-derived organoids demonstrates potential of drug repurposing for rare cystic fibrosis genotypes

Eyleen de Poel, Sacha Spelier, Marne C. Hagemeijer et al. · Journal of Cystic Fibrosis · 2023 · 42 citations · Full text

Medicine, Molecular Medicine, Drug Discovery +15

Forskolin-induced organoid swelling is associated with long-term cystic fibrosis disease progression

Danya Muilwijk, Eyleen de Poel, Peter van Mourik et al. · European Respiratory Journal · 2022 · 41 citations · Full text

Life Sciences, Pathobiology, Physiology +14