Eyleen de Poel

CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank

Maarten H. Geurts, Eyleen de Poel, Gimano D. Amatngalim et al. · Cell stem cell · 2020 · 212 citations · Full text

Engineering, Medicine, Genetics +10

Evaluating CRISPR-based prime editing for cancer modeling and CFTR repair in organoids

Maarten H. Geurts, Eyleen de Poel, Cayetano Pleguezuelos‐Manzano et al. · Life Science Alliance · 2021 · 130 citations · Full text

Human Organoids, Engineering, Genetics +16

Comparison of ex vivo and in vitro intestinal cystic fibrosis models to measure CFTR-dependent ion channel activity

Domenique D. Zomer-van Ommen, Eyleen de Poel, Evelien Kruisselbrink et al. · Journal of Cystic Fibrosis · 2018 · 52 citations

Fibrosis, Molecular Physiology, Medicine +9

Functional Restoration of CFTR Nonsense Mutations in Intestinal Organoids

Eyleen de Poel, Sacha Spelier, S.W.F. Suen et al. · Journal of Cystic Fibrosis · 2021 · 38 citations · Full text

FDA-approved drug screening in patient-derived organoids demonstrates potential of drug repurposing for rare cystic fibrosis genotypes

Eyleen de Poel, Sacha Spelier, Marne C. Hagemeijer et al. · Journal of Cystic Fibrosis · 2023 · 37 citations · Full text

Fibrosis, Fda-approved Drug Screening, Pharmacology +5