Topology and Membrane Anchoring of the Coronavirus Replication Complex: Not All Hydrophobic Domains of nsp3 and nsp6 Are Membrane Spanning

Monique Oostra, Marne C. Hagemeijer, Michiel van Gent, +4

Journal of Virology

Virus StructureCoronavirus Replication ComplexLarge Replicase PolyproteinsViral ReplicationMembrane Anchoring +11

Membrane rearrangements mediated by coronavirus nonstructural proteins 3 and 4

Marne C. Hagemeijer, Iryna Monastyrska, Janice Griffith, +7

Virology

Membrane RearrangementsViral ReplicationMolecular BiologyVirologyViral Structural Protein +2

The Coronavirus Nucleocapsid Protein Is Dynamically Associated with the Replication-Transcription Complexes

Monique H. Verheije, Marne C. Hagemeijer, Mustafa Ulaşlı, +4

Journal of Virology

Replication-transcription ComplexesViral ReplicationSystems BiologyN ProteinDynamically Associated +11

Dynamics of Coronavirus Replication-Transcription Complexes

Marne C. Hagemeijer, Monique H. Verheije, Mustafa Ulaşlı, +5

Journal of Virology

Visualizing Coronavirus RNA Synthesis in Time by Using Click Chemistry

Marne C. Hagemeijer, Annelotte M. Vonk, Iryna Monastyrska, +2

Journal of Virology

Mobility and Interactions of Coronavirus Nonstructural Protein 4

Marne C. Hagemeijer, Mustafa Ulaşlı, Annelotte M. Vonk, +3

Journal of Virology

Comparison of ex vivo and in vitro intestinal cystic fibrosis models to measure CFTR-dependent ion channel activity

Domenique D. Zomer-van Ommen, Eyleen de Poel, Evelien Kruisselbrink, +6

Journal of Cystic Fibrosis

FibrosisMolecular PhysiologyMedicinePhysiologyGastroenterology +7

FDA-approved drug screening in patient-derived organoids demonstrates potential of drug repurposing for rare cystic fibrosis genotypes

Eyleen de Poel, Sacha Spelier, Marne C. Hagemeijer, +22

Journal of Cystic Fibrosis

FibrosisFda-approved Drug ScreeningPharmacologyPulmonary FibrosisDrug Development +3

Forskolin-induced organoid swelling is associated with long-term cystic fibrosis disease progression

Danya Muilwijk, Eyleen de Poel, Peter van Mourik, +22

European Respiratory Journal

High-throughput functional assay in cystic fibrosis patient-derived organoids allows drug repurposing

Sacha Spelier, Eyleen de Poel, Georgia N. Ithakisiou, +8

ERJ Open Research